AI and Discovery

Creative Collision: What AI Is Changing About How Bets and Breakthroughs Happen

Creative breakthroughs can come from unexpected connections between disciplines, new tech intertwining with old problems, and signals arriving from adjacent fields.AI is transforming discovering new and adjacent opportunities without most of us noticing. This session explored how founders, researchers, and investors can intentionally own their unique Discovery sources and stay at the generative edge of what's next.
Date: May 21, 2026
Location: Luskin Conference Center, UCLA
Organizer: UCLA Technology Transfer Group
Speaker: Dr. Gigi Louisa Johnson

What this session explored

The session explored a practical question for founders, researchers, investors, and organizational leaders: when AI systems increasingly pre-filter what people see, search, share, and consider, how can teams preserve the messy, cross-domain discovery work that leads to original bets and breakthroughs? The talk framed AI not only as a productivity layer, but as a discovery and uncertainty layer that can narrow consideration sets unless people deliberately design human-AI-human systems around it.

Event Information

Originally presented during LABest Bioscience Day, hosted by UCLA Technology Development Group

Official Session Description

Creative breakthroughs come from collision: unexpected connections between disciplines, new tech intertwining with old problems, and signals arriving from adjacent fields. AI is reshaping the conditions that make those collisions possible. It changes what we encounter, how we think, what gets filtered before we ever see it. This session explores how founders, researchers, and investors can intentionally stay at the generative edge of what's next.

Post-Event Briefing and Key Takeaways

`Creative Collision` examined how AI is reshaping the front end of discovery: what people see, what sources they trust, what teams bring into the room, and how quickly consideration sets can converge before human judgment begins.

The talk connected three pressures. First, generative tools are flooding information environments with more content, more synthetic output, and more polished but uneven material. Second, AI search and overview systems are changing how people encounter information, often answering before a person reaches the original source. Third, enterprise and team AI practices are becoming uneven and invisible: each person may be using different tools, defaults, searches, and information pathways without the group ever examining those differences.

Against that backdrop, the session argued for designing unique discovery and uncertainty systems, not only knowledge systems. Knowledge systems retrieve and synthesize what is already legible. Uncertainty systems help people hold weak signals, unresolved tensions, and cross-domain collisions long enough for new possibilities to emerge.

The talk introduced practices such as Discovery Dig, Signal Garden, Discovery Accelerator, and Real Options Canvas as ways to make discovery more deliberate. These practices ask teams to audit inbound flows, notice where consensus is flattening thought, preserve fragile signals, and experiment with non-obvious possibilities before the opportunity has been pre-approved by a filter no one designed or can fully see.

For Rethink Next, the larger question is not simply whether teams are using AI. It is whether teams understand how AI is shaping what they notice, what they ignore, and how they work together around uncertainty.

Key Takeaways

- AI is changing discovery before decisions begin, not just accelerating work after decisions are made.
- Teams need to examine their information inputs, search practices, and AI defaults as part of the work itself.
- Discovery systems should preserve weak signals and cross-domain collisions instead of filtering them out too early.
- Boundary spanners remain critical because they carry ambiguity, uncertainty, and translation across domains.
- Knowledge systems and uncertainty systems solve different problems; organizations need both.
- A deliberate human-AI-human discovery system can help teams protect what makes their thinking different.

Presentations and Resources

The LABest slide deck introduced The Narrowing, the flood and flattening of AI-mediated information environments, boundary-spanning discovery, and a set of Rethink Next practices for building unique human-AI-human discovery systems.
Session materials available from this event.
Type: Talk, Conference Session
Track: Discovery
Status: Past

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